The T-cell lymphomas account for approximately 5%–10% of all NHL.
- More common in Asia, 10-20% of NHL.
The median age at diagnosis is 59 years, which is lower than the median age of 66 for patients with NHL in general.
Male:female = 2:1.
Globally the three most common subtypes of PTCL are PTCL-NOS (25.9%), AITL (18.5%), and ALCL (12%).
- PTCL-NOS more common in North America.
- AITL and EATL more common in Europe.
The median time from diagnosis to relapse or progression of disease after primary therapy was 6.7 months.
The median overall survival and second progression-free survival were only 5.5 and 3.1 months, respectively.

Incidence

Pathobiology